Case series: Five pediatric germ cell/sex cord stroma tumors
نویسندگان
چکیده
منابع مشابه
The role of surgical management in pediatric germ cell tumors (GCTs), NCI case series.
PURPOSE To review the experience of a tertiary referral center in pediatric germ cell tumors (GCTs) in the last 8 years and to investigate the impact of surgery and site of disease on prognosis. PATIENTS AND METHODS We retrospectively analyzed the cases of pediatric germ cell tumors at National Cancer Institute over an 8 years period. Data concerning diagnosis, surgery and medical decisions w...
متن کاملPediatric Germ Cell Tumors: A Developmental Perspective
Germ cell tumors (GCTs) arising in infants, children, and adolescents present a set of special challenges. GCTs make up about 3% of malignancies in children aged 0-18 and nearly 15% of cancers in adolescents. Epidemiologic and molecular evidence suggests that GCTs in young children likely represent a distinct biologic group as compared to GCTs of older adolescents and adults. Despite this diffe...
متن کاملPediatric malignant germ cell tumors show characteristic transcriptome profiles.
Malignant germ cell tumors (GCT) of childhood are rare and heterogeneous neoplasms thought to arise from primordial germ cells. They vary substantially in their natural history and show important clinical differences from their adult counterparts. To address the biological basis for these observations, we have undertaken a comprehensive analysis of global gene expression patterns in pediatric m...
متن کاملPediatric Germ Cell Tumors; A 10-year Experience
OBJECTIVE The aim of this study was to evaluate the outcome of germ cell tumors in patients admitted to our center during a ten year period. METHODS In a retrospective descriptive study, patients with the pathological diagnosis of germ cell tumor (GCT) were included. All records were evaluated and patients followed by personal visit in clinic or phone call. Data regarding age, sex, tumor site...
متن کاملPediatric central nervous system germ cell tumors: a review.
Central nervous system (CNS) germ cell tumors (GCTs) represent approximately 3% of primary pediatric brain tumors and encompass a wide pathologic spectrum. CNS GCTs are most commonly located in the pineal and suprasellar regions of the brain and can be divided into major groups including germinomas and nongerminomatous GCTs (NGGCTs), with teratomas often considered a separate category. The clin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Medicine and Surgery
سال: 2019
ISSN: 2049-0801
DOI: 10.1016/j.amsu.2018.11.011